Expression study of liver smaples of 2-days old Mfp2 knockout mice as compared to wild type

Study on gene expression in multifunctional protein 2 deficient mice. Liver samples of two days old mice in normal conditions are used. In total 8 arrays were hybridized corresponding to 4 KO mice and 4 WT mice Results: Cholesterol synthesis is induced and ppar alpha targets also differentially expressed between KO and WT.

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Martens K, Ver Loren van Themaat E, van Batenburg MF, Heinäniemi M, Huyghe S, Van Hummelen P, Carlberg C, Van Veldhoven PP, Van Kampen A, Baes M