The effect of soluble CD74 (sCD74) and recombinant macrophage migration inhibitory factor (MIF) treatment on the gene expression profile in cardiac myofibroblasts

GSE108999

Mus musculus

12 Downloadable Samples

Affymetrix Mouse Clariom S Array (clariomsmouse)

Submitter Supplied Information

Description

Co-treatment with soluble CD74 and MIF induced necroptosis in cardiac myofibroblasts. The underlying mechanism of sCD74/MIF-induced necroptosis are still unkown. We used a microarray to identify pathways regulated by co-treatment with sCD74 and MIF .

PubMed ID

30371153

Publication Title

Soluble CD74 Reroutes MIF/CXCR4/AKT-Mediated Survival of Cardiac Myofibroblasts to Necroptosis.

Total Samples

Submitter’s Institution

RWTH Aachen University

Authors

Soppert J, Kraemer S, Beckers C, Averdunk L, Möllmann J, Denecke B, Goetzenich A, Marx G, Bernhagen J, Stoppe C

Source Repository

Gene Expression Omnibus (GEO)

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