github link
Accession IconGSE119650

Transcriptomes of microglia in experimental cerebral malaria in mice in the presence and absence of Type I Interferon signaling

Organism Icon Mus musculus
Sample Icon 22 Downloadable Samples
Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Submitter Supplied Information

Description
Plasmodium berghei ANKA infection in mice is used as a model for human cerebral malaria, the most severe complication of Plasmodium falciparum infection. The response of brain cells such as microglia has been little investigated, and may play a role in the pathogenesis or regulation of cerebral malaria. We showed previously that microglia are activated in P. berghei infections, and that Type 1 Interferon signaling is important for activation. This dataset contains the transcriptome of brain microglia of infected mice in the presence and absence of Type I interferon signaling, with the aim of identifying the genes involved in this pathway in microglia during experimental cerebral malaria. Refererence: Capuccini et al 2016, Scientific Reports, 6:39258
PubMed ID
Total Samples
22
Submitter’s Institution

Samples

Show of 0 Total Samples
Filter
Add/Remove
Accession Code
Title
Sex
Specimen part
Treatment
Processing Information
Additional Metadata
No rows found
Loading...