Expression data from E0771 mouse mammary tumor cell line and its derivative with high metastatic potential

A distinct type of macrophages helps breast cancer cells to overcome rate-limiting steps in the metastatic process and establish lethal metastatic tumors. Since only a minor population of cancer cells can establish macroscopic metastatic tumors, we hypothesized that this metastatic cancer cell population have higher expression of receptors for macrophage-derived ligands compared to their parental cells.

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Kitamura T, Kato Y, Brownlie D, Soong DYH, Sugano G, Kippen N, Li J, Doughty-Shenton D, Carragher N, Pollard JW