Effects of calorie restriction and exercise on mammary gland gene expression in C57BL/6 mice

We performed a factorial experiment examining the effects of calorie restriction (CR) and exercise (EX) in mice. CR mice received 70% of calories but 100% of all other nutrients compared to AL mice. Food consumption, weight gain, and physical activity levels were recorded for 6 weeks.

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Padovani M, Lavigne JA, Chandramouli GV, Perkins SN, Barrett JC, Hursting SD, Bennett LM, Berrigan D