Gene Expression Changes Induced by Bacterial Superantigen, Staphylococcal Enterotoxin B

Toxic shock syndrome (TSS) is an acute, serious systemic illness caused by bacterial superantigens (BSAg). We characterized the early molecular events underlying TSS using our HLA-DR3 transgenic mouse model and studied gene expression profiling using DNA microarrays.

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Rajagopalan G, Tilahun AY, Asmann YW, David CS