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Accession IconGSE18879

Effects of dynamic compressive loading on MSC chondrogenesis

Organism Icon Bos taurus
Sample Icon 6 Downloadable Samples
Technology Badge Icon Affymetrix Bovine Genome Array (bovine)

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Long-term dynamic compression enhanced the mechanical properties of MSC-seeded constructs only when loading was initiated after 21 days of chondrogenic differentiation. This study examined the molecular differences of chondrogenic MSCs compared to undifferentiated MSCs (TGF-beta vs no TGF-beta) and the effects of dynamic loading on MSC chondrogenesis (loading vs free-swelling).
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