siRNA-mediated Egr-3 knockdown in VEGF-treated HUVEC

GSE18913

Homo sapiens

21 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Analysis of umbilical vein endothelial cells (HUVEC) treated with Egr-3 siRNA under the VEGF treatment for 0,1, and 4 h. Egr-3, a member of early growth response family, is immediately and dramatically induced by VEGF in HUVEC, which regulates expression of many genes related to endothelial activation.

PubMed ID

19965691

Publication Title

Vascular endothelial growth factor activation of endothelial cells is mediated by early growth response-3.

Total Samples

Submitter’s Institution

Kyorin University School of Medicine

Authors

Suehiro J, Hamakubo T, Kodama T, Aird WC, Minami T

Source Repository

Gene Expression Omnibus (GEO)

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