Expression data from WT and TCF-1-deficient memory CD8 T cells

TCF-1 is an HMG family transcription factor which is known to be activated by the canonical Wnt signaling pathway and modulated by other signals such as those derived from T cell receptor. We found that during CD8 T cell responses, TCF-1 deficiency impaired long-term maintenance of antigen-specific memory CD8 T cells.

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Zhou X, Yu S, Zhao DM, Harty JT, Badovinac VP, Xue HH