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Accession IconGSE30802

Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming

Organism Icon Homo sapiens
Sample Icon 26 Downloadable Samples
Technology Badge Icon Affymetrix Human Genome U133B Array (hgu133b), Affymetrix Human Genome U133A Array (hgu133a)

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Aims/hypothesis: Duct cells isolated from adult human pancreas can be reprogrammed to express islet beta cell genes by adenoviral transduction of the developmental transcription factor neurogenin3 (Ngn3). In this study we aimed to fully characterize the extent of this reprogramming and intended to improve it.
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