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Accession IconGSE37359

Genome-wide expression profiling analysis of a Sphingomyelin Synthase 1 mutant mouse model

Organism Icon Mus musculus
Sample Icon 22 Downloadable Samples
Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

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Description
Lysosomal storage diseases are congenital lipid metabolism disorders, often accompaning by male infertility. Sms1, the enzyme, that generates sphingomyelin from ceramides seems to be involved in spermatogeneis and spermiogenesis. Therefore, testis but also muscle and brain of a mouse line carrying an insertional mutation in Sms1 were analysed.
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