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Accession IconGSE40734

The effect on gene expression of Smchd1 deletion in primary MEFs, transformed MEFs and MEF tumours

Organism Icon Mus musculus
Sample Icon 11 Downloadable Samples
Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

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Description
Smchd1 appears to act as a tumour suppressor in the transformed fibroblast model. We find gene expression differences are most pronounced in the transformed MEFs. We always detect a small number of clustered genes and imprinted genes as differentially expressed, along with others involved in tumorigenesis.
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