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Accession IconGSE40880

The effect on gene expression of Smchd1 deletion in end stage lymphomas

Organism Icon Mus musculus
Sample Icon 12 Downloadable Samples
Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

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Smchd1 appears to act as a tumour suppressor in the E-Myc B cell lymphoma model. We find gene expression differences are most pronounced in the premalignant cells, and observe more variability in end stage lymphomas. We always detect a small number of clustered genes and imprinted genes as differentially expressed, along with others involved in tumorigenesis.
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