gene expression profiling of NFIA deficient mice brain

Background. Nuclear factor I-A (NFI-A), a phylogenetically conserved transcription/replication protein, plays a crucial role in mouse brain development. Previous studies showed that disruption of the Nfia gene in mice leads to perinatal lethality, corpus callosum agenesis, and hydrocephalus.

12

Wong YW, Schulze C, Streichert T, Gronostajski RM, Schachner M, Tilling T