Pre-leukemic Cebpa mutant myeloid progenitors

GSE47813

Mus musculus

12 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

In this study, we use pre-malignant cells from different Cebpa mutant acute myeloid leukemia (AML) models. We have used conditional KO models (CreLoxP) and isolated hematopoietic cells shortly after induction of recombination, in order to look at pre-leukemic cells, which have acquired the first hit, but not yet undergone full malignant transformation.

PubMed ID

23831605

Publication Title

Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors.

Total Samples

Submitter’s Institution

Finsenlaboratoriet

Authors

Schuster MB, Frank AK, Bagger FO, Rapin N, Vikesaa J, Porse BT

Source Repository

Gene Expression Omnibus (GEO)

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