Identification of Lrig3 target genes in Xenopus animal caps injected with wnt3a and chordin

GSE50487

Xenopus laevis

8 Downloadable Samples

Affymetrix Xenopus laevis Genome 2.0 Array (xlaevis2)

Submitter Supplied Information

Description

During embryonic development, the neural crest is a transient, migratory cell population that differentiates into a large variety of tissues and contributes much to the formation of vertebrate body. In Xenopus, lrig3 is involved in neural crest formation by modulating FGF and Wnt signaling. Lrig3 functions downstream of pax3 and zic1 to regulate the expression of neural crest markers.

PubMed ID

26198637

Publication Title

The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling.

Total Samples

Submitter’s Institution

The Chinese University of Hong Kong

Authors

Wang C, Kam RK, Shi W, Xia Y, Chen X, Cao Y, Sun J, Du Y, Lu G, Chen Z, Chan WY, Chan SO, Deng Y, Zhao H

Source Repository

Gene Expression Omnibus (GEO)

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