Expression data from periplaque regions in multiple sclerosis spinal cord

There have been few studies that have focused on the periplaque regions surrounding demyelinated plaques, especially in spinal cords. Areas of incomplete demyelination have been demonstrated but poorly studied. The present study aimed to analyze the molecular immunopathology of periplaque demyelinated lesions (PDLs) in the spinal cord of patients with secondary progressive multiple sclerosis (MS).

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Lieury A, Chanal M, Androdias G, Reynolds R, Cavagna S, Giraudon P, Confavreux C, Nataf S