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Accession IconGSE56063

Expression data from EMyc;Prdm11 WT and EMyc;Prdm11 KO end-stage splenic tumors

Organism Icon Mus musculus
Sample Icon 18 Downloadable Samples
Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

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Description
The PR-domain family (PRDMs) encodes transcriptional regulators, several of which are deregulated in cancer. We found that loss of Prdm11 accelerates MYC-driven lymphomagenesis in the E-Myc mouse model.
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