Effect of PARP1 inhibition on transcription in MCF7 cells

Analysis of the role of PARP1 in gene transcription in MCF7 cells under non-stress conditions. The hypothesis was that PARP1 activity in MCF7 cells plays a role in gene transcription. The results indicate that PARP1 inhibition does not significantly affect transcription after 6 hours of treatment.

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Krukenberg KA, Jiang R, Steen JA, Mitchison TJ