Transcript profiling of mouse 4T1 tumors grown in preirradiated vs. nonirradiated mammary tissue

The present study was designed to identify genes induced by irradiation in the 4T1 breast cancer model mimicking aggressive local relapse after radiotherapy. For this purpose, we obtained the transcriptomes of 4T1 tumors grown in either preirradiated (IRR+4T1) or non-irradiated (4T1) mammary tissue.

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Asparuhova MB, Secondini C, Rüegg C, Chiquet-Ehrismann R