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Accession IconGSE6532

Definition of clinically distinct molecular subtypes in estrogen receptor positive breast carcinomas using genomic grade

Organism Icon Homo sapiens
Sample Icon 737 Downloadable Samples
Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a), Affymetrix Human Genome U133B Array (hgu133b), Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

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Purpose: A number of microarray studies have reported distinct molecular profiles of breast cancers (BC): basal-like, ErbB2-like and two to three luminal-like subtypes. These were associated with different clinical outcomes. However, although the basal and the ErbB2 subtypes are repeatedly recognized, identification of estrogen receptor (ER)-positive subtypes has been inconsistent. Refinement of their molecular definition is therefore needed.
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