GSE69252Gene expression profiling in NK cells of patients infected with Leishmania mexicana
Homo sapiens
18 Downloadable Samples
Affymetrix Human Gene 1.0 ST Array (hugene10st)Submitter Supplied Information
Description
The aim of this study was to identify differences in the NK-cell response towards Leishmania mexicana lipophosphoglycan (LPG) between patients with localized (LCL) and diffuse (DCL) cutaneous leishmaniasis through gene expression profiling, in an attempt to pinpoint alterations in the signaling pathways responsible for the NK-cell dysfunction in patients with DCL.
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18
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NK cells LCL patient non stimulated, biological rep 2
human nk cells from pbmc
lcl
lcl
non stimulated
NK cells control non stimulated, biological rep 4
human nk cells from pbmc
control
control
non stimulated
NK cells LCD patient non stimulated, biological rep 2
human nk cells from pbmc
dcl
dcl
non stimulated
NK cells LCL patient non stimulated, biological rep 1
human nk cells from pbmc
lcl
lcl
non stimulated
NK cells control LPG-stimulated 6h, biological rep 3
human nk cells from pbmc
control
control
leishmania mexicana lpg 20g/ml 6 hours
NK cells control non stimulated, biological rep 3
human nk cells from pbmc
control
control
non stimulated
NK cells LCD patient LPG-stimulated 6h, biological rep 1
human nk cells from pbmc
dcl
dcl
leishmania mexicana lpg 20g/ml 6 hours
NK cells control non stimulated, biological rep 1
human nk cells from pbmc
control
control
non stimulated
NK cells control non stimulated, biological rep 2
human nk cells from pbmc
control
control
non stimulated
NK cells LCL patient LPG-stimulated 6h, biological rep 2
human nk cells from pbmc
lcl
lcl
leishmania mexicana lpg 20g/ml 6 hours
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