Expression data from intestinal mucosa of Zucker rats

Obesity is a chronic, complex and multifactorial disease that has reached pandemia levels and is becoming a serious health problem. Intestinal microbiota is considered a main factor that affects body weight and fat mass, which points toward a critical role in the development of obesity. In this sense, probiotic bacteria might modulate the intestinal microbiota and the mucosal-associated lymphoid tissue. The aim of this study was to investigate the effects of L. paracasei, L. rhamnosus and B. breve feeding on the intestinal mucosa gene expression in a genetic animal model of obesity.

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Plaza-Díaz J, Robles-Sánchez C, Abadía-Molina F, Morón-Calvente V, Sáez-Lara MJ, Ruiz-Bravo A, Jiménez-Valera M, Gil Á, Gómez-Llorente C, Fontana L