Genome wide comparison of the inducible transcriptomes of CAR, PXR and PPAR in primary human hepatocytes

GSE76148

Homo sapiens

24 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

To identify the CAR-, PXR- and PPAR-specific genome-wide expression changes, hepatocyte cultures from six individual donors were treated with the prototypical ligands for

PubMed ID

26994748

Publication Title

Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.

Total Samples

Submitter’s Institution

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology

Authors

Kandel BA, Thomas M, Winter S, Damm G, Seehofer D, Burk O, Schwab M, Zanger UM

Source Repository

Gene Expression Omnibus (GEO)

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