mTOR and HDAC inhibitors converge on the TXNIP/thioredoxin pathway to cause catastrophic oxidative stress and regression of RAS-driven tumors - refine.bio

GSE84205

Homo sapiens

12 Downloadable Samples

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Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

mTOR and HDAC inhibitors induce cell death of malignant peripheral nerve sheath tumors (MPNSTs) in vitro, and in vivo

PubMed ID

Publication Title

mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors.

Total Samples

12

Submitter’s Institution

Harvard Medical School - Brigham Women's Hospital

Authors

Malone CF, Emerson C, Ingraham R, Barbosa W, Guerra S, Yoon H, Liu LL, Michor F, Haigis M, Macleod KF, Maertens O, Cichowski K

Source Repository

Gene Expression Omnibus (GEO)

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