Analysis of Aire effects on individual mice of different genetic backgrounds

GSE8564

Mus musculus

19 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

We compared gene expression profiles of aire-deficient and wild-type littermate thymic medullary epithelial cells. This was done in order to determine whether Aire's effects differed among strains, and also among individuals of the same strain.

PubMed ID

18838677

Publication Title

The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription.

Total Samples

Submitter’s Institution

Harvard Medical School

Authors

Venanzi ES, Melamed R, Mathis D, Benoist C

Source Repository

Gene Expression Omnibus (GEO)

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