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Accession IconGSE8948

Effect of loss of CREB and CREM on cocaine-induced gene expression in the striatum

Organism Icon Mus musculus
Sample Icon 55 Downloadable Samples
Technology Badge Icon Affymetrix Murine Genome U74A Version 2 Array (mgu74av2), Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

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Description
Ablation of the Creb1 gene in forebrain neurons was performed using the Cre/loxP system, with the recombinase expressed from the Camk2alfa promoter. Mice were crossed into the Crem KO background to prevent compensation of CREB loss by CREM overexpression.
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