Gene expression data for HEK-293T cells transfected with GFP control and plant derived DNA demethylase DME

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GSE96863

Homo sapiens

6 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Expression profiles of human embryonic kidney (HEK)-293T cells expressing a GFP (293T-GFP) or a truncated form of Arabidopsis DEMETER (DME) 5-methylcytosine (5mC) DNA glycosylase (293T-DME) analyzed on an Affymetrix Human Genome U133 Plus 2.0 Array Platform. These array data revealed differentially expressed genes (DEGs) between the 293T-GFP cells (without direct 5mC excision activity) and 293T-DME cells (with artificially implemented direct 5mC excision activity).

PubMed ID

28831075

Publication Title

DEMETER plant DNA demethylase induces antiviral response by interferon signalling in animal cells.

Total Samples

Submitter’s Institution

Seoul National University

Authors

Mok YG, Choi KY, Hong SH, Huh JH

Source Repository

Gene Expression Omnibus (GEO)

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