Systematic RNA-seq analysis of the early events of CD4+ T cell activation

RNA-seq was used to look at the transcriptome changes and the early events of T cell receptor stimulation in CD4+ T cells Overall design: CD4+ T cells were stimulated with immobilised anti-CD3/CD28 antibodies for 4 hours and RNA was extracted and subjected to RNA-seq analysis.

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Hutchins AP, Poulain S, Fujii H, Miranda-Saavedra D