Differences in miRNA Detection Levels are Technology and Sequence Dependent [NGS]

We undertook an integrative technological approach to compare miRNA detection capability of three high-throughput commercial platforms. Overall design: We artificially introduced human precursor, 2’-O-methyl modified and mature spiked-in miRNAs in a controlled fashion into native human placenta total RNA.

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Leshkowitz D, Horn-Saban S, Parmet Y, Feldmesser E