Comparison between lamina propria macrophages and muscularis macrophages

Lamina propria and muscularis macrophages, were sorted at steady steate and 2h after oral exposure to an attenuated form of Salmonella, comparison among these populations showed that the muscularis macrophages quckly respond to the presence of intestinal bacteria, upregulating some important tissue protective genes. Overall design: intestinal macrophages from 3 mice were pooled into one RNA sample, the experiment was done control X infected and was repeated twice

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Gabanyi I, Muller PA, Feighery L, Oliveira TY, Costa-Pinto FA, Mucida D