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Accession IconSRP167870

Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

Organism Icon Homo sapiens
Sample Icon 20 Downloadable Samples
Technology Badge IconIllumina HiSeq 2500

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Description
Using RNA-seq to identify gene expression changes after genetic deletion of ADAR Overall design: RNA-seq of A549, HCC366, NCI-H1650, and NCI-H196 cells after CRISPR-Cas9-mediated deletion of ADAR as compared to a control gene. A549 cells were also treated with vehicle or interferon-ß for 24 hours prior to collection for RNA-seq.
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20
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