Description

The transcription factor MIST1 is required for final maturation of secretory cells of diverse tissues, including gastric digestive-enzyme secreting zymogenic (chief) cells (ZCs). Here, we show that MIST1 directly activates RAB26, RAB3D and several other genes.

Publication Title

RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation.

Sample Metadata Fields

Specimen part, Cell line