The aim of the experiment was to identify genes rapidly responding at their expression level to enhanced expression of the transcription factor GRF9.
GROWTH-REGULATING FACTOR 9 negatively regulates arabidopsis leaf growth by controlling ORG3 and restricting cell proliferation in leaf primordia.
Age, Specimen part
View SamplesWe found a new spontaneous mutant mouse, laggard, characterized by general weakness in movements and retardation in growth.
Kif14 mutation causes severe brain malformation and hypomyelination.
Specimen part
View SamplesTarget gene of mineralocorticoid receptor (MR) is comparatively unknown, although distal convoluted tubule (DCT) expresses MR in in vivo.
Genome-wide analysis of murine renal distal convoluted tubular cells for the target genes of mineralocorticoid receptor.
Cell line, Treatment
View SamplesGene expression analysis to compare control cells and sorted cells
Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis.
Specimen part
View SamplesAnalysis of HEK293T cells overexpressing ZAPS (zinc finger antiviral protein, short form; NP_078901), which is a member of the PARP (poly (ADP-ribose) polymerase)-superfamily. Results of gene profiles provide insight into the role of ZAPS in innate immunity.
ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses.
Specimen part, Cell line
View SamplesRat mast cell line RBL-2H3 was analyzed to investigate the molecular mechanism of Dectin-1-mediated activation and responses of mast cells.
Dectin-1-mediated signaling leads to characteristic gene expressions and cytokine secretion via spleen tyrosine kinase (Syk) in rat mast cells.
Specimen part, Cell line
View SamplesTo investigate the evolutionary divergence of transcriptional regulation between the mouse subspecies, we performed transcriptome analysis by microarray on testes from the X-chromosome substitution strain, which carries different subspecies-derived X chromosome on the host subspecies genome. Transcription profiling showed that large-scale aberrations in gene expression were occurred on the introgressed X chromosome. This improper expression was restored by introducing chromosome 1 from the same donor strain as the X chromosome, suggesting that the genetic incompatibility between trans-acting regulatory gene(s) on chromosome 1 and X-linked downstream genes might be a cause of the misregulation.
Evolutionarily diverged regulation of X-chromosomal genes as a primal event in mouse reproductive isolation.
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.
No sample metadata fields
View SamplesTo investigate genes that might influence resistance to infection through IGF1R, we screened human breast cancer-derived OCUB-M cells transfected with expression vector encoding IGF1R using microarray analysis.
Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.
No sample metadata fields
View SamplesTo identify genes that influence resistance to mastitis, we scanned
Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.
No sample metadata fields
View Samples