Description

Microarray was used to delineate the global gene expression profile underlying the specific developmental program of two divergent antigen-specific T helper subsets (Th22 versus Th17) by identifying upregulation or downregulation of key lineage-determining transcription factors, cytokines, chemokines and other genes that govern their functional attributes.

Publication Title

Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria.

Sample Metadata Fields

Specimen part