A predictive gene list for response to high dose melphalan therapy in patients diagnosed with multiple myeloma is generated by combining results from dose response experiments and microarray data using a B-cell line panel and the introduction of multivariate regression techniques.
Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines.
Cell line
View SamplesThis SuperSeries is composed of the SubSeries listed below.
A model system for assessing and comparing the ability of exon microarray and tag sequencing to detect genes specific for malignant B-cells.
Cell line
View SamplesThe purpose of this study was to develop a quantification method that can be used to assess the ability of exon microarray to detect malignant B-cell transcripts.
A model system for assessing and comparing the ability of exon microarray and tag sequencing to detect genes specific for malignant B-cells.
Cell line
View SamplesThis SuperSeries is composed of the SubSeries listed below:
Diffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis.
Specimen part
View SamplesBackground
No associated publication
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
A multiple myeloma classification system that associates normal B-cell subset phenotypes with prognosis.
Specimen part, Disease
View SamplesObjectives: In patients with tonsil squamous cell cancer (TSCC), radiation-therapy (RT) induce mucositis, which is clinically challenging with limited prophylactic interventions and no predictive tests. In a pilot study set-up, we performed global gene-expression analysis on human oral mucosa tissue and blood cells to identify differential expressed genes involved in mucositis pathogenesis.
No associated publication
Specimen part, Disease, Disease stage, Treatment, Time
View SamplesGene expression profiling was performed for 28 DLBCL primary clinical samples and assignment of activated B-cell-like(ABC)/germinal center B-cell-like (GCB) DLBCL classes, B-cell-associated gene signature (BAGS), and a probability of response to doxorubicin was performed for each sample.
High miR-34a expression improves response to doxorubicin in diffuse large B-cell lymphoma.
Specimen part, Disease stage, Treatment
View SamplesPurpose
Diffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis.
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Molecular classification of tissue from a transformed non-Hogkin's lymphoma case with unexpected long-time remission.
Sex, Specimen part
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