It has been shown that tumor infiltrating immune cells have a profound impact on the outcome of FL. To find mechanisms whereby TILs are altered gene expession analysis of highly pure TILs were performed.
Follicular lymphoma cells induce changes in T-cell gene expression and function: potential impact on survival and risk of transformation.
Specimen part, Subject
View SamplesThis SuperSeries is composed of the SubSeries listed below.
A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma.
Sex, Age, Specimen part
View SamplesAlternative splicing is a key event to human transcriptome and proteome diversity and complexity. Recent evidence suggests that pancreatic cancer might possess particular patterns of splice variation that influence the function of individual genes contributing to tumour progression in this disease. The identification of new pancreatic cancer-associated splice variants would offer opportunities for novel diagnostics and potentially also represent novel therapeutic targets.
A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma.
Sex, Age, Specimen part
View SamplesAlternative splicing is a key event to human transcriptome and proteome diversity and complexity. Recent evidence suggests that pancreatic cancer might possess particular patterns of splice variation that influence the function of individual genes contributing to tumour progression in this disease. The identification of new pancreatic cancer-associated splice variants would offer opportunities for novel diagnostics and potentially also represent novel therapeutic targets.
Splice variants as novel targets in pancreatic ductal adenocarcinoma.
Sex, Age, Specimen part
View SamplesIn order to define the targets of two miRNA overexpressed in NK cells in CFS/ME paitents, miRNA precursors for hsa-miR-99b and hsa-miR-330-3p were transfected in to buffy coat derived Natural Killer cells isolated by negative magnetic selection.
MicroRNAs hsa-miR-99b, hsa-miR-330, hsa-miR-126 and hsa-miR-30c: Potential Diagnostic Biomarkers in Natural Killer (NK) Cells of Patients with Chronic Fatigue Syndrome (CFS)/ Myalgic Encephalomyelitis (ME).
Specimen part, Disease, Disease stage
View SamplesEnvironmental enrichment has been shown to induce wholescale alterations to the gene expression profile of experimental animals
The impact of environmental enrichment on the murine inflammatory immune response.
Sex, Age
View SamplesExpression profiling of MRC5, IFN gamma treated MRC5 and PGF cells.
Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex.
No sample metadata fields
View SamplesEffects of lack of functional LH receptor and/or a constitutively active FSH receptor on gene expression in the ovaries of female mice were studied. The results suggest that transgenic expression of the mouse Fshr in granulosa cells leads to abnormal ovarian structure/function and infertility. This finding indicates that gain-of-function mutations of the Fshr in female mice bring about distinct and clear changes in ovarian function.
No associated publication
Sex, Age, Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Comparative expression analysis reveals lineage relationships between human and murine gliomas and a dominance of glial signatures during tumor propagation in vitro.
Sex, Age, Specimen part, Disease stage
View SamplesIn this study, we screened a cohort of 57 paediatric brain tumours, with a wide range of pathologies to identify gene expression profiles
Comparative expression analysis reveals lineage relationships between human and murine gliomas and a dominance of glial signatures during tumor propagation in vitro.
Sex, Age, Specimen part, Disease stage
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