Transcriptional profiling of mouse Prostate cancer cells comparing Pbsn-Cre LSL-KrasG12D P53L/L cells with Pbsn-Cre LSL-BrafV600E P53L/L cells, and to determine the effects of Kras or Braf mutantion on murine PCa gene expression.
No associated publication
No sample metadata fields
View SamplesAnalysis of primary PDAC cells established from Pdx-1CreAPCL/+p53L/L and Pdx-1Crep53L/L mice.
APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice.
Specimen part
View SamplesTranscriptional profiling of mouse Pancreatic cancer cells comparing Pdx1-Cre LSL-KrasG12D TGIF1L/L P53L/L cells with Pdx1-Cre LSL-KrasG12D P53L/L cells, and to determine the effects of TGIF1 deletion on PDAC gene expression.
No associated publication
No sample metadata fields
View SamplesWe obtained snap-frozen tissue samples from 20 colorectal cancer (CRC) patients with stage III disease who had undergone curative resection. The expression profiles were determined using Affymetrix Human Genome U133Plus 2.0 arrays.
ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development.
No sample metadata fields
View SamplesNine groups of rat tongue epithelia and submucosal fibroblasts RNA samples respectively, including three from normal control, three from dysplasia, and three from carcinoma (3 rats per group) were collected for gene microarray hybridization.
Modulation of IL-1β reprogrammes the tumor microenvironment to interrupt oral carcinogenesis.
Specimen part, Disease
View SamplesThis SuperSeries is composed of the SubSeries listed below.
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Specimen part, Cell line
View SamplesKeratinocytes are the major constituent of epithelial cells at mucosal surfaces and skin, which cover organs, internal cavities and the body. Traditionally, keratinocytes have been considered as an inert component of the multilayered epithelium to protect the subepithelial compartments from the pathogenic microorganisms, toxic stimuli and physical trauma. However, accumulated researches of the airway, gastrointestinal tract and skin have demonstrated that keratinocytes function in the development of the immune system, promotion of pathologic inflammation and even impose diverse decisions on immune cells.
Genome-wide analysis reveals the active roles of keratinocytes in oral mucosal adaptive immune response.
Specimen part, Time
View SamplesNine groups of rat tongue tissue RNA samples, including three from normal control, three from 4NQO induced tongue tissue, and three from 4NQO induced and IL-1Ra interference tongue tissue (3 rats per group) were collected for gene microarray hybridization.
Modulation of IL-1β reprogrammes the tumor microenvironment to interrupt oral carcinogenesis.
Specimen part, Treatment
View SamplesOral squamous cell carcinoma cell line Cal27 was transfected with lentiviral shIL-1beta or scrambled shRNA.
Modulation of IL-1β reprogrammes the tumor microenvironment to interrupt oral carcinogenesis.
Cell line
View SamplesWe used microarrays to detail the global gene expression in cell line with or without RHOQ knock-down.
No associated publication
Specimen part, Cell line
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