Human Notch1 intracellular domain (NICD) was overexpressed in human primary lymphatic endothelial cells (LECs) for 10 and 24 hours by adenovirus. A GFP-control adenovirus-infected cells (24hours) and uninfected cells were also analysed as controls.
An exquisite cross-control mechanism among endothelial cell fate regulators directs the plasticity and heterogeneity of lymphatic endothelial cells.
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Gene body methylation can alter gene expression and is a therapeutic target in cancer.
Sex, Cell line, Treatment, Time
View SamplesDemethylation treatment reduce gene body methylation as well as gene expression
Gene body methylation can alter gene expression and is a therapeutic target in cancer.
Cell line, Treatment, Time
View SamplesRNA-seq study of tumors that develop in mice after injection of gastric carcinoma cell line, AGS, with or without Epstein-Barr virus infection
No associated publication
Sex, Specimen part, Disease, Cell line
View SamplesRNA-Seq study of tumors that develop in mice after injection of nasopharyngeal carcinoma (NPC) cell line C666.1 and the xenograph tumors C15 and C17
No associated publication
Sex, Specimen part, Disease, Cell line
View Samplesthe goal of this study are to reveal potential functions of novel lncRNAs in PDLSCs ,systematicly characterize PDLSC related lncRNAs and protein coding genes in uPDLSCs,dPDLSCs and TNF-a-dPDLSCs with Next Generation Sequencing.
No associated publication
Sex, Specimen part, Treatment
View SamplesMesenchymal stromal cells (MSCs), which have immunosuppressive and trophic abilities that are induced by inflammatory cytokines, have emerged as a promising option for cell-based therapy. The cytokine profiles vary substantially across different diseases and stages of disease progression, which has been shown to influence the curative properties of MSCs. Our knowledge about how MSCs respond systemically to cytokines is still limited. Here, we individually stimulated MSCs in vitro with IFN-?and used RNA-Seq to analyze their expression profiles.
No associated publication
Sex, Specimen part
View SamplesTranscriptome analysis of MCF-7 cells exposed for 48 hours to various concentrations of xenoestrogen chemicals.
Expressomal approach for comprehensive analysis and visualization of ligand sensitivities of xenoestrogen responsive genes.
Cell line
View SamplesAnalysis of 143 completely histologically-normal breast tissues resulted in the identification of a malignancy risk gene signature that may serve as a marker of subsequent risk of breast cancer development.
Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue.
No sample metadata fields
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Complementary strand microRNAs mediate acquisition of metastatic potential in colonic adenocarcinoma.
Sex
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