Quantifying impact of lead on cytokine production and gene expression in PBMCs
No associated publication
Specimen part
View SamplesWhen compared to skin, oral mucosal wounds heal rapidly and with reduced scar formation. This study used an Affymetrix microarray platform to compare the transcriptomes of oral mucosa and skin wounds in order to identify critical differences in the healing response at these two sites.
Positional differences in the wound transcriptome of skin and oral mucosa.
Sex, Specimen part
View Samplesanalyzed changes in cytokine/chemokine production and gene expression levels in, human peripheral blood mononuclear cells upon teratment with 15M,2,4-benzenetriol
Identification of human cell responses to benzene and benzene metabolites.
No sample metadata fields
View SamplesSphingosine Kinase-1 knock out protects against hyperoxic lung injury
No associated publication
Treatment
View SamplesCD4+ cells from Foxp3.eGFP mice containing Foxp3- Teff and Foxp3+ Treg cells were treated with anti-CD3/CD28 monoclonal antibodies or soluble OX40L and JAG1 for 3 days to induce TCR-dependent vs TCR-independent Treg proliferation. Untreated fresh CD4+ T-cells used as control. Post treatment T-cell proliferation was confirmed by Cell Trace violet dilution and Foxp3+ (Treg) and Foxp3-(Teff) were sorted. Differential gene expression profiling between Tregs and Teff cells among control, anti-CD3/CD28 and OX40L-JAG1 treated cultured was performed using affymetrix mouse gene 2.0 ST micro array.
OX40L-JAG1-Induced Expansion of Lineage-Stable Regulatory T Cells Involves Noncanonical NF-κB Signaling.
Specimen part, Treatment
View SamplesThe morphology and the behavior of skin and oral tissue keratinocytes are different. One significant dissimilarity between the two sites is the response to injury. Oral and skin keratinocytes have intrinsic differences in the response to injury and such differences are reflected in gene expression profiles.
No associated publication
Specimen part
View SamplesArylsulfatase B (ARSB; N-acetylgalactosamine-4-sulfatase) null mouse hepatic gene expression was compared with control C57BL/6J mice
No associated publication
Sex, Age
View SamplesResting and proliferating Treg cells from NOD mice G-BMDC-Treg co-cultures were sorted out and anlyzed for differential gene expresion pattern.
No associated publication
Specimen part
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