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Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.
Specimen part, Cell line
View SamplesAnalysis of cellular response to DHODH inhibition at gene expression and nuclear/cytoplasmic distribution level.
Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.
Specimen part
View SamplesAnalysis of cellular response to DHODH inhibition at gene expression and nuclear/cytoplasmic distribution level.
Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.
Specimen part
View SamplesAnalysis of cellular response to DHODH inhibition at gene expression and nuclear/cytoplasmic distribution level.
Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.
Specimen part
View SamplesTranscriptional analysis of the effects of the deletion of the sRNAs glmY and glmZ in EHEC
Global analysis of posttranscriptional regulation by GlmY and GlmZ in enterohemorrhagic Escherichia coli O157:H7.
No sample metadata fields
View SamplesObjective: We hypothesized that type 1 diabetes (T1D) is accompanied by changes in gene expression in peripheral blood mononuclear cells (PBMCs) due to dysregulation of adaptive and innate immunity, counterregulatory responses to immune dysregulation, insulin deficiency and hyperglycemia. Research Design and Methods: Microarray analysis was performed on PBMCs from 43 patients with newly diagnosed T1D, 12 patients with newly diagnosed type 2 diabetes (T2D) and 24 healthy controls. One and four month follow-up samples were obtained from 20 of the T1D patients.
Gene expression in peripheral blood mononuclear cells from children with diabetes.
Sex, Age, Treatment, Race
View SamplesWnt9b is expressed in the ureteric bud of the kidney at all stages of development. In Wnt9b mutants, the ureteric bud forms but the metanephric mesenchyme is never induced to undergo differentiation.
Myc cooperates with β-catenin to drive gene expression in nephron progenitor cells.
Specimen part
View SamplesWnt9b is expressed in the ureteric bud of the kidney at all stages of development. The Wnt9b cneo allele functions as a partial loss of function. Wnt9bcneo/cneo mutant kidneys initially develop normally but exhaust their nephron progenitor cells by E15.5. Here, we have compared expression between Wnt9bcneo/+ and Wnt9bcneo/cneo kidneys. Additional urogenital tissue (adrenal glands, reproductive tracts and bladder) may have been included in some samples.
No associated publication
Specimen part
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